Ranibizumab in retinal vein occlusion: treatment recommendations by an expert panel
Identifieur interne : 000222 ( Main/Exploration ); précédent : 000221; suivant : 000223Ranibizumab in retinal vein occlusion: treatment recommendations by an expert panel
Auteurs : Heinrich Gerding [Suisse] ; Jordi Monés [Espagne] ; Ramin Tadayoni [France] ; Francesco Boscia [Italie] ; Ian Pearce [Royaume-Uni] ; Siegfried Priglinger [Autriche]Source :
- The British Journal of Ophthalmology [ 0007-1161 ] ; 2014.
Abstract
Retinal vein occlusion (RVO) is a common cause of retinal vascular disease, resulting in potentially irreversible loss of vision despite the existence of several therapeutic options. The humanised monoclonal antibody fragment ranibizumab binds to and inhibits vascular endothelial growth factor, a key driver of macular oedema in RVO. In 2010, ranibizumab was approved in the USA for the treatment of macular oedema in RVO and, in 2011, ranibizumab was approved in the European Union for the treatment of visual impairment caused by macular oedema secondary to RVO in branch and central RVO. Ranibizumab provides an additional therapeutic option for this complex disease: an option that was not fully considered during the preparation of current international guidelines. An expert panel was convened to critically evaluate the evidence for treatment with ranibizumab in patients with visual impairment caused by macular oedema secondary to RVO and to develop treatment recommendations, with the aim of assisting physicians to optimise patient treatment.
Url:
DOI: 10.1136/bjophthalmol-2014-305041
PubMed: 25075121
PubMed Central: 4345884
Affiliations:
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Monés</name><affiliation wicri:level="1"><nlm:aff id="af3"><institution>Institut de la Màcula i de la Retina, Centro Médico Teknon and Barcelona Macula Foundation</institution>,<addr-line>Barcelona</addr-line>,<country>Spain</country></nlm:aff><country xml:lang="fr">Espagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Tadayoni, Ramin" sort="Tadayoni, Ramin" uniqKey="Tadayoni R" first="Ramin" last="Tadayoni">Ramin Tadayoni</name><affiliation wicri:level="1"><nlm:aff id="af4"><addr-line>Department of Ophthalmology</addr-line>,<institution>Hôpital Lariboisière, Université Paris Diderot—Sorbonne Paris Cité, AP-HP</institution>,<addr-line>Paris</addr-line>,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Boscia, Francesco" sort="Boscia, Francesco" uniqKey="Boscia F" first="Francesco" 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wicri:level="1"><nlm:aff id="af7"><addr-line>Department of Ophthalmology</addr-line>,<institution>General Hospital (AKH)</institution>,<addr-line>Linz</addr-line>,<country>Austria</country></nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">The British Journal of Ophthalmology</title><idno type="ISSN">0007-1161</idno><idno type="eISSN">1468-2079</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Retinal vein occlusion (RVO) is a common cause of retinal vascular disease, resulting in potentially irreversible loss of vision despite the existence of several therapeutic options. The humanised monoclonal antibody fragment ranibizumab binds to and inhibits vascular endothelial growth factor, a key driver of macular oedema in RVO. In 2010, ranibizumab was approved in the USA for the treatment of macular oedema in RVO and, in 2011, ranibizumab was approved in the European Union for the treatment of visual impairment caused by macular oedema secondary to RVO in branch and central RVO. Ranibizumab provides an additional therapeutic option for this complex disease: an option that was not fully considered during the preparation of current international guidelines. An expert panel was convened to critically evaluate the evidence for treatment with ranibizumab in patients with visual impairment caused by macular oedema secondary to RVO and to develop treatment recommendations, with the aim of assisting physicians to optimise patient treatment.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct></biblStruct><biblStruct></biblStruct><biblStruct><analytic><author><name sortKey="Shahid, H" uniqKey="Shahid H">H Shahid</name></author><author><name sortKey="Hossain, P" uniqKey="Hossain P">P Hossain</name></author><author><name sortKey="Amoaku, Wm" uniqKey="Amoaku W">WM Amoaku</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Rehak, M" uniqKey="Rehak M">M Rehak</name></author><author><name sortKey="Wiedemann, P" uniqKey="Wiedemann P">P Wiedemann</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Awdeh, Rm" uniqKey="Awdeh R">RM Awdeh</name></author><author><name 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Jampol</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Autriche</li><li>Espagne</li><li>France</li><li>Italie</li><li>Royaume-Uni</li><li>Suisse</li></country></list><tree><country name="Suisse"><noRegion><name sortKey="Gerding, Heinrich" sort="Gerding, Heinrich" uniqKey="Gerding H" first="Heinrich" last="Gerding">Heinrich Gerding</name></noRegion></country><country name="Espagne"><noRegion><name sortKey="Mones, Jordi" sort="Mones, Jordi" uniqKey="Mones J" first="Jordi" last="Monés">Jordi Monés</name></noRegion></country><country name="France"><noRegion><name sortKey="Tadayoni, Ramin" sort="Tadayoni, Ramin" uniqKey="Tadayoni R" first="Ramin" last="Tadayoni">Ramin Tadayoni</name></noRegion></country><country name="Italie"><noRegion><name sortKey="Boscia, Francesco" sort="Boscia, Francesco" uniqKey="Boscia F" first="Francesco" last="Boscia">Francesco Boscia</name></noRegion></country><country name="Royaume-Uni"><noRegion><name sortKey="Pearce, Ian" sort="Pearce, Ian" uniqKey="Pearce I" first="Ian" last="Pearce">Ian Pearce</name></noRegion></country><country name="Autriche"><noRegion><name sortKey="Priglinger, Siegfried" sort="Priglinger, Siegfried" uniqKey="Priglinger S" first="Siegfried" last="Priglinger">Siegfried Priglinger</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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